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While resetting depends on the phase response curve and, therefore, varies within the circadian cycle and also in the course of the scotophase, the so-called photic shutoff can take place at any timepoint within the scotophase and depends only on light intensity, duration of light exposure and spectral quality, but not substantially on the circadian phase.

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What we do know is that the melatonin parents are purchasing at drug and health-food stores to help their children sleep is a synthetic form of a hormone that our brains naturally produce to help us fall asleep.

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Melatonin is a natural hormone segregated by the body and melatonin levels generally increase in the dark at night.

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Other Substances -- Caffeine, tobacco, and alcohol can all diminish levels of melatonin in the body while cocaine and amphetamines may increase melatonin production.

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Some evidence suggests that melatonin may help promote sleep in children with ADHD or autism, although it does not seem to improve the behavioral symptoms of ADHD or autism.

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Melatonin appears to regulate aromatase, but the concentrations at which it does this may be more likely to prevent an age-related deficiency, rather than act as a pharmacological intervention that would be used with testosterone supplements.

In fact, in various studies conducted by Georges Maestroni throughout the 1980s (when melatonin research was still somewhat new), he decided to remove the pineal glands of various animals and see what would happen.

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